3-HO-PCE (3-Hydroxyeticyclidine)

Description

Advanced Research with 3-HO-PCE (3-Hydroxyeticyclidine)

3-HO-PCE, or 3-Hydroxyeticyclidine, is a prominent research chemical within the arylcyclohexylamine family and a structural derivative of PCE (Eticyclidine). It is chemically defined by the presence of a hydroxyl group at the meta (3-position) of the phenyl ring. In specialized research settings, 3-HO-PCE serves as a vital molecular probe for studying how the introduction of a phenolic hydroxy group—which significantly increases hydrogen-bonding potential—modifies binding affinity at the NMDA receptor compared to its parent compound or methoxylated analogues.

As an $N$-ethyl derivative, 3-HO-PCE provides essential data for researchers mapping the steric and electronic requirements of ligand-binding sites. This reagent is particularly valuable for investigating the “structure-activity relationship” (SAR) of hydroxylated arylcyclohexylamines and their hypothesized cross-affinity with various neurochemical transporters. When you buy 3-HO-PCE in the USA through USA Professor, you are securing a professional-grade reagent refined for high-fidelity structural profiling, ligand-binding assays, and forensic calibration.

Technical Integrity & Laboratory Storage

• Phenolic Structural Platform: 3-HO-PCE features a 3-hydroxyl substitution, offering a unique platform for Investigating the pharmacophore requirements of $N$-ethyl phenolic arylcyclohexylamines.

• Verified Analytical Purity: Our 3-HO-PCE is rigorously batch-tested to meet a purity standard of >97%, ensuring a clean profile for HPLC, GC-MS, and NMR spectroscopy.

• Hydrochloride (HCl) Stability: Provided as a hydrochloride salt, this reagent offers superior crystalline stability and resistance to atmospheric degradation compared to freebase forms.

• Optimal Stability: 3-HO-PCE remains chemically stable for up to 2 years when stored in the correct environment. Like all phenolic compounds, it is sensitive to heat, moisture, and oxidation. Store in a cool, dry, and dark location in an airtight container to maintain chemical integrity.

• Rapid USA Fulfillment: Avoid the logistical complexities and risks of international chemical shipping. All orders are processed and dispatched from our domestic USA facility, ensuring a secure and efficient supply chain for your research laboratory.

Technical Specifications

• Full IUPAC Name: 3-(1-(ethylamino)cyclohexyl)phenol hydrochloride

• Synonyms: 3-Hydroxyeticyclidine, 3-HO-PCE

• CAS Number: 2243815-20-3

• Molecular Formula: $C_{14}H_{21}NO \cdot HCl$

• Molar Mass: 255.8 g/mol

• Purity: >97%

• Form: Hydrochloride (HCl) Salt

Laboratory Safety & Handling Protocols

Warning: This product is intended strictly for laboratory research and forensic applications only. It is not for human or animal consumption.

• Inhalation: In the event of accidental inhalation, move the subject to fresh air immediately and ensure they remain in a position comfortable for breathing.

• Eye Contact: If the material enters the eyes, rinse gently with water for at least five minutes. Remove contact lenses if present and easy to do.

• Skin Contact: Wash the affected area thoroughly with soap and water. Use appropriate PPE, including gloves and lab coats, during all handling procedures.

• Environmental Responsibility: Discharge of research chemicals into the environment is prohibited. Dispose of all waste and residues in accordance with federal, state, and local hazardous material regulations.